The 2000–01 Notre Dame Fighting Irish men's basketball team represented the University of Notre Dame during the 2000–01 NCAA Division I men's basketball season.
They finished the regular season with a record of 20–10, 11-5.
In the Second Round, they lost to the #3 seed Ole Miss, 59–56.
This was Mike Brey's first year at Notre Dame.
Forward Troy Murphy was the team's captain and leading scorer, averaging 21.8 points per game.