Pitt scored first on a 72-yard touchdown pass from John Turman to Antonio Bryant, taking an early 7–0 lead.
Iowa State answered with a 23-yard pass from Sage Rosenfels to Chris Anthony, tying the game at 7, at the end of the 1st quarter.
Sage Rosenfels threw his second touchdown pass of the game, a 9 yarder to Chris Anthony, as Iowa State made it 27–7 at halftime.
In the third quarter, Pitt quarterback Rod Rutherford scored on a 2-yard touchdown run, making it 27–14.
Iowa State's Carl Gomez kicked a 41-yard field goal to cap the scoring at 37–29.