The 2016 Pinstripe Bowl was a post-season American college football bowl game played on December 28, 2016 at Yankee Stadium in the New York City borough of the Bronx.
The seventh edition of the Pinstripe Bowl featured the Pittsburgh Panthers of the Atlantic Coast Conference against the Northwestern Wildcats of the Big Ten Conference.
It was one of the 2016–17 bowl games that concluded the 2016 FBS football season.
This was the seventh meeting between the schools, with the series previously tied at 3–3.
The previous meeting of the two teams was on September 29, 1973, where the Panthers defeated the Wildcats by a score of 21–14.