The 2000 Vuelta a Castilla y León was the 15th edition of the Vuelta a Castilla y León cycle race and was held on 31 July to 4 August 2000.

The race started in Valladolid and finished in Bembibre.

[2][3] The race was won by Francisco Mancebo.

Fifteen teams of up to eight riders started the race:[3]

This cycling race article related to Spanish cycling is a stub.