rookies in italics 53 active, 9 inactive, 3 practice squad The Colts suffered the second losing season of Peyton Manning's career.
After opening with dominant wins over the Jets and Buffalo, the Colts were crushed twice in three games by the Patriots with a loss to Oakland in between.
Two more wins followed to bring the Colts to 4–3, but they followed this up with two more losses heading into their matchup with the San Francisco 49ers at home on November 25.
Manning threw four interceptions, two to Ahmed Plummer and two more to Zack Bronson including one that was returned for a touchdown.
During the press conference, a reporter asked Mora a question about the Colts' playoff chances now that the team was 4–6.
When the question was repeated, Mora responded by dismissing the suggestion that the Colts could make the postseason in the following manner: What's that?