The 2001 season was the Minnesota Vikings' 41st in the National Football League (NFL).

Before the end of the season, the team fired head coach Dennis Green, who had become a polarizing force among the Vikings fan base despite his successful coaching tenure with the team.

Mike Tice coached the final game of 2001, a loss to the Baltimore Ravens.

This was the first season since 1989 that defensive tackle John Randle was not on the opening day roster.

The season began in tragic circumstances when offensive tackle Korey Stringer died of heatstroke in training camp.

Some season highlights included a 35–13 win over the rival Green Bay Packers in Week 6, and a Week 10 victory over the New York Giants in which Randy Moss pulled in 10 receptions for 171 yards and three touchdowns leading to a 28–16 victory.