The 2001 Pennsylvania 500 presented by Pep Boys was the 20th stock car race of the 2001 NASCAR Winston Cup Series and the 29th iteration of the event.

The race was held on Sunday, July 29, 2001, in Long Pond, Pennsylvania, at Pocono Raceway, a 2.5 miles (4.0 km) triangular permanent course.

[4] Ricky Rudd, driving for Robert Yates Racing, would set the fastest time in the session, with a lap of 53.163 and an average speed of 169.291 miles per hour (272.447 km/h).

[4] Jeff Gordon, driving for Hendrick Motorsports, would set the fastest time in the session, with a lap of 54.341 and an average speed of 165.621 miles per hour (266.541 km/h).

[4] Jeff Gordon, driving for Hendrick Motorsports, would set the fastest time in the session, with a lap of 54.859 and an average speed of 164.057 miles per hour (264.024 km/h).

[8] Todd Bodine, driving for Haas-Carter Motorsports, would win the pole, setting a time of 52.840 and an average speed of 170.325 miles per hour (274.112 km/h).