Marat Safin was unsuccessful in his title defence, being defeated in the semifinals by Pete Sampras in a rematch of the 2000 final, while Venus Williams was successful in her title defense, beating her sister Serena in the women's final.

20-year-old Australian Lleyton Hewitt won the men's title, defeating Sampras in the final.

It was the second consecutive US Open final defeat for Sampras.

Tomáš Berdych / Stéphane Bohli defeated Brendan Evans / Brett Joelson, 6–4, 6–4.

Galina Fokina / Svetlana Kuznetsova[a] defeated Jelena Janković[b] / Matea Mezak, 7–5, 6–3.