The 2004 Campeonato Nacional Apertura Copa Banco del Estado was the 75th Chilean League top flight, in which Universidad de Chile won its twelfth league title after beating Cobreloa in the final, on penalties, with goalkeeper Johnny Herrera scoring the winning penalty kick.
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Deportes Temuco and Universidad de Chile qualified as best losers.
Played on June 28 & July 4, 2004 Played on July 7 & 10, 2004 *Qualified due to its better Apertura 2004 position Played on July 21 & 25, 2004 *Qualified due to its better Apertura 2004 position
Santiago Wanderers & Universidad de Concepción qualified to 2004 Copa Sudamericana