[1] Backup quarterback Chad Hutchinson was benched and cut after struggling heavily in the next two preseason games against the Indianapolis Colts and Buffalo Bills.
Rookie running back Cedric Benson held out of training camp over a contract dispute until just before the final preseason game.
Despite all these setbacks, the Bears were still hopeful because franchise middle linebacker Brian Urlacher had made it through the preseason in good health, unlike the year before when he battled injuries all season, beginning with a pulled hamstring on the first day of training camp.
[4] The Saints scored first on a John Carney field goal, but the Bears struck back with a Kyle Orton to Justin Gage touchdown pass.
After the Saints scored on an Aaron Brooks touchdown pass to Donté Stallworth, Robbie Gould tied the game on a 35-yard field goal.
Orton eventually threw a 22-yard pass to Muhsin Muhammad to set up a game-winning field goal from Gould with six seconds left in the game.
The Saints' last chance to march 65 yards to win was crushed when Brooks' pass to Az-Zahir Hakim was intercepted by Nathan Vasher.
[5] In the first quarter, Bears running back Thomas Jones went out with an injury, but his backups Adrian Peterson and Cedric Benson combined for 137 yards and a touchdown.
Things were bad from the beginning for the Bears, who allowed a 58-yard Jake Delhomme TD pass to Steve Smith just 55 seconds into the game.
The spark provided by the offense was short-lived, as midway through the 3rd quarter, Delhomme went deep to Steve Smith again, this time for a 39-yard touchdown that put the Panthers up 23–14.