The 2005 Conference USA men's basketball tournament was held March 9–12 at the FedExForum in Memphis, Tennessee.
The Cardinals, in turn, received an automatic bid to the 2005 NCAA tournament.
They were joined in the tournament by fellow C-USA members UAB, Charlotte, and Cincinnati, all of whom earned at-large bids.
The two teams with the worst conference records were not invited to the tournament.
All remaining tournament seeds were determined by regular season conference records.