The 2005 Mississippi State Bulldogs baseball team won the SEC tournament and placed second at the Miami Regional at the 2005 NCAA Division I baseball tournament.

Ron Polk was the coach of the Bulldogs, in his 26th year.

The Bulldogs closed out the regular season with a 36–20 record and an SEC record of 13-16.

The Bulldogs defeated LSU, South Carolina, Tennessee, and Ole Miss en route to their 5th SEC Tournament victory.

The Bulldogs were the 2 seed in the Miami regional, but lost twice to Miami and were eliminated.