Porto's victory in the 2005–06 Primeira Liga, qualified them for the 2006 Supertaça Cândido de Oliveira and the 2006–07 UEFA Champions League group stage.

Porto won their first piece of silverware of the season by winning the Supertaça Cândido de Oliveira against Vitória de Setúbal.

[3] Jesualdo Ferreira would be appointed as manager shortly afterwards, after Rui Barros had been appointed caretaker manager after Dutch coach Co Adriaanse left the club in August.

The Portistas would be eliminated in the following round, the first knockout round, by English side Chelsea who were led at the time by former Porto coach José Mourinho.

[5][6] In the last game of the league season, the Azuis e Brancos would claim a twenty-second league title after a 4–1 home victory over Desportivo das Aves.