The 2006 Chicago Cubs season was the 135th season of the Chicago Cubs franchise, the 131st in the National League and the 91st at Wrigley Field.

The Cubs finished with a record of 66–96 in last place of the National League Central.

Chicago was managed by Dusty Baker.

Infielders Outfielders Coaches Note: Pos = Position; G = Games played; AB = At bats; H = Hits; Avg.= Batting average; HR = Home runs; RBI = Runs batted in Note: G = Games played; AB = At bats; H = Hits; Avg.= Batting average; HR = Home runs; RBI = Runs batted in Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; S0 = Strikeouts Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts Note: G = Games pitched; W = Wins; L = Losses; SV = Saves; ERA = Earned run average; SO = Strikeouts [4]