The team's head coach was Ron Prince, in his first year at K-State after leaving his offensive coordinator position at Virginia.
Driving 47 yards in just over 5 minutes, Drone hit a wide open Pierre Jackson in the corner of the end zone to pull within 24-23 with 3:02 to go.
Drone dropped back to pass but was quickly swallowed by the Kansas State defensive line to preserve the victory.
McKinney sprinted to his right and went 88 yards down the sideline for Kansas State's first game-opening score since Red Elder's touchdown return in a 6-6 tie at Oklahoma on Nov. 7, 1936.
Dylan Meier threw for 125 yards and two touchdowns for the Wildcats (2-0), who extended their winning streak against Sun Belt teams to 10 straight games.
Kansas State's defense dominated for the second straight game and forced three turnovers, and the Wildcats' offense found its groove late in a 23-7 victory over Marshall.
Kansas State outgained the Thundering Herd 355 yards to 142, but didn't mount a sustained TD drive until late in the fourth quarter.
In the end, Kansas State held the high-octane Cardinal offense to their fewest passing yards in 15 games, but it wasn’t enough to derail Louisville.
Hunter Cantwell threw for 173 yards, including a 19-yard touchdown to Harry Douglas to cap a 97-yard drive on Louisville's opening possession of the game.
The K-State defense settled in and held the Cardinals to just 87 yards the rest of the half as Louisville took a 10-0 lead into the locker room, thanks to a 25-yard Art Carmody field goal with 4:17 to go in the second quarter.
The Wildcats were unable to dent the scoreboard until early in the fourth quarter, when Clayton ripped off a 69-yard run for K-State's only points of the game.
Kansas State won the battle of the stat sheet but was unable to turn yards into points as the Wildcats dropped a 17-3 decision at Baylor to open Big 12 play at Floyd Casey Stadium.
In the closing seconds, Watts broke up what would have been a game-winning catch by D'Juan Woods then intercepted Bobby Reid's tipped pass in the end zone as time ran out.
Nebraska gambled and won on a pair of tricky fourth-down calls, beating Kansas State 21-3 snapping the 21st-ranked Cornhuskers' four-game losing streak in Manhattan.
And on the Cornhuskers' first drive of the second quarter, Zac Taylor's 24-yard bootleg on fourth-and-2 from Kansas State's 27 set up a 3-yard TD pass to Josh Mueller—also a backup tight end—for a 14-0 lead.
Linebacker Brandon Archer recovered a muffed punt and a fumble for Kansas State which broke a two-game losing streak.
Texas' Colt McCoy got pinned under the pile on the first drive at the goal line and came up favoring his right shoulder after a crushing hit by Wildcat linebacker Brandon Archer.
Kansas State had a tough day on the gridiron, turning the ball over six times (all six were credited to Josh Freeman, including three fumbles and three interceptions).
Josh Freeman, the freshman sensation who accounted for four touchdowns in the previous week's upset of Texas, was manhandled by a Kansas pass defense ranked 117th in the country.
16 Rutgers for 30 minutes, but the Scarlet Knights scored 20 unanswered points in the second half to hand the Wildcats a 37-10 loss in the inaugural Texas Bowl before 52,210 fans at Reliant Stadium.