The play-off round of 2006 UEFA European Under-21 Championship qualification was held on 11–13 and 15–16 November 2005.
Winners of play-off round qualified to the championship played following year in May and June, where Portugal was chosen to host the fixtures.
[1] Germany won 3–0 on aggregate France won 3–2 on aggregate Italy won 2–1 on aggregate Serbia and Montenegro won 5–2 on aggregate Denmark won 4–1 on aggregate Netherlands won 2–0 on aggregate Ukraine won 5–4 on aggregate Portugal won 3–2 on aggregate