West Virginia fullback Owen Schmitt scored on a 3-yard run midway through the third quarter to cap a 66-yard drive that was set up by an interception by freshman Quinton Andrews.
Pat White threw for a TD and ran for another while Darius Reynaud scored twice, including a 96-yard kickoff return, for the Mountaineers (3–0), who extended their winning streak to 10 games, second in the nation to TCU's 12 in a row.
With scouts from 15 NFL teams in attendance, West Virginia took a 38–10 halftime lead in beating Maryland (2–1) for the third straight year, the first time that has happened since 1996–98.
Maryland, which had wins over Division I-AA William & Mary and unheralded Middle Tennessee State, watched as the Mountaineers compiled more than 300 yards rushing for the third straight game.
The Pirates held Slaton, who entered as the nation's third-leading rusher, to 80 yards—less than half of his 168-yard average—and afterward he said he was bothered by cramps blamed on the hot, humid weather.
West Virginia led just 17–10 early in the fourth quarter when White flipped a pass to Reynaud, who zigzagged 60 yards back across the field and through the Pirates' defense for the clinching touchdown.
White capped West Virginia's opening drive with a 5-yard touchdown run, then flipped his scoring pass to Schmitt early in the second quarter to snap a 7-all tie.
Steve Slaton bailed out the Mountaineers (5–0) with 185 yards and a touchdown and Pat White rushed for two scores as West Virginia pulled away late to extend the nation's second-longest winning streak to 12 games.
But the defense needed two late interceptions deep in Mountaineers territory to secure the win as West Virginia kept three drives by Mississippi State (1–5) alive with penalties.
White and Schmitt scored two touchdowns apiece and Slaton constantly stung what had been considered a stout Bulldogs rush defense with nine runs of 10 yards or more.
The Mountaineers opened the second half with a commitment to Slaton, who carried the ball five times and capped a 10-play scoring drive with a 10-yard touchdown that made it 21–7 with 10:22 left in the third quarter.
The Bulldogs did manage a late score on a 1-yard dive by Anthony Dixon with 5:31 remaining in the game, but the Mountaineers answered with a long drive and Schmitt's second touchdown from 5 yards out to make it 35–14.
White led West Virginia (7–0, 2–0 Big East) on two one-play drives, running 45 yards for a touchdown in the second quarter, and throwing a 52-yard scoring pass to Rayshawn Bolden in the third.
Pat McAfee added three field goals, including a career-long 48-yarder, as West Virginia tied Ohio State for the longest winning streak in the nation.
Brohm threw for 354 yards and a touchdown, and the Cardinals took advantage of key mistakes by West Virginia to earn the signature win they've so desperately sought under coach Bobby Petrino and stake their claim as a serious contender for the Bowl Championship Series title game.
The Cardinals avenged 2005's triple-overtime loss to West Virginia (7–1, 2–1) by returning a fumble and a punt for touchdowns during a pivotal three-minute stretch in the third quarter.
Heisman Trophy hopeful Steve Slaton ran for 156 yards and a touchdown for West Virginia, but fumbled on consecutive snaps in the third quarter—bothered by a broken left wrist.
Brohm connected with Mario Urrutia on a 7-yard TD pass and Anthony Allen added a 5-yard touchdown run to keep the Cardinals safely in front.
Set back by their own mistakes, the Mountaineers simply couldn't keep pace as their school-record 14-game winning streak ended while a packed Papa John's Stadium crowd—clad mostly in black T-shirts that read "Beat WVU" – stormed the field.
West Virginia, the nation's second leading rushing offense, compiled 313 yards against Cincinnati, one of the best run defenses which had surrendered five TDs entering the game.
The Mountaineers (9–1, 4–1 Big East) beat their biggest rival for the fourth time in five seasons, though not quite as easily as in last year's 45–13 romp in Morgantown in which White and Slaton combined for 399 of West Virginia's 451 yards rushing.
White, the sophomore option quarterback whose quickness again was too much for Pitt to handle, threw for 204 yards and hit Slaton on the running back's first two touchdown receptions this season.
The only problem was Revis' return left West Virginia with plenty enough time to score, with White hitting Slaton for 67 yards on their second pass play touchdown of the half.
West Virginia got the ball back at the South Florida 28 after a punt and White found a leaping Myles with a 15-yard TD pass in the left corner of the end zone.
He later converted a pair of third-down passes to keep alive a 14-play drive that resulted in an 18-yard field goal by Delbert Alvarado midway through the fourth and a 24–12 lead.
15 West Virginia knocked down Mike Teel's 2-point conversion pass in the end zone to preserve the Mountaineers' 41–39 triple-overtime win over No.
Jarrett Brown ran for one touchdown and threw the go-ahead score in triple overtime to help West Virginia (10–2, 5–2 Big East) cap its second straight 10-win season.
A loser for so long, the Scarlet Knights started 9–0 before being upset at Cincinnati, then rebounded by beating Syracuse to set the stage for what would have been a historic win against WVU.
On the 2-point try, Teel scrambled to his right and threw toward Rice but Vaughn Rivers broke up the pass and several thousand fans in the sellout crowd ran onto the field in celebration.
Johnson leapt between two West Virginia defenders and in front of a third for a 32-yard reception in the third quarter of the Gator Bowl, one of his nine catches for 186 yards and two touchdowns in Georgia Tech's 38–35 loss.