Kejuan Jones and Renaldo Works led the Oklahoma rushing attack into the BCS National Championship Game.

Oklahoma featured Heisman Trophy winner Jason White quarterbacking the high-powered Sooner offense, which scored over 42 points per game.

[4] In 2004, Choice was named the Sooners' starting running back out of spring practice, but a left hamstring pull sidelined him and allowed true freshman Adrian Peterson to move ahead of him on the depth chart in the fall.

At the end of the season, his mother fell ill and Choice applied for a medical hardship to return home and play for Georgia Tech.

Choice, along with All-American Calvin Johnson and senior quarterback Reggie Ball, took Tech to the Atlantic Coast Conference Title Game as the Coastal Division Champions.

[7][8] Choice led the Yellow Jackets' powerful ground game behind four returning starters on the offensive line and veteran fullback Mike Cox.

As the reigning ACC Rushing Champion, Choice looked to improve upon 2006's nine-win season, with new offensive coordinator John Bond featuring the single back formation.

He also missed part of the tenth game Duke University when he re-injured his right hamstring, but was able to return to the contest in the second quarter.

He concluded his NCAA career on the "Smurf Turf" of Boise against the Fresno State Bulldogs in the Humanitarian Bowl.

He did not receive another carry until week 7 against the St. Louis Rams, after he replaced fellow rookie Felix Jones as the backup running back, who had suffered a torn hamstring against the Arizona Cardinals in week 6 and later a season ending torn ligament in his left toe during his recovery process.

[23] In 2010, during the season opener he fumbled with four seconds left in the first half, which led to a Washington Redskins' touchdown as time expired that proved to be the difference in the game.

Although the call was heavily criticized, after the incident he would not see much action during the team's second worst start in franchise history (one win in their first eight games), that eventually cost the job of head coach Wade Phillips.

[24] After Jones suffered a sprained ankle, he was named the starting running back in the week 7 game against the St. Louis Rams, but Murray had a performance for the ages, breaking several league and franchise rushing records.

Choice was waived on October 29, with the team deciding to give a bigger role to undrafted rookie Phillip Tanner.

He was released on November 22, after being deactivated in two contests with a hamstring injury and appearing in one game against his former team, the Dallas Cowboys, in which he only gained seven rushing yards.

The Buffalo Bills claimed Choice off waivers on November 23, 2011, reuniting him with his former Georgia Tech head coach Chan Gailey.

He replaced an injured Fred Jackson and was the backup to C. J. Spiller, playing in six games, while rushing for 70 yards and one touchdown.

He re-signed with the Bills for a second time on March 29, 2013,[26] and was later released on December 4, with the team opting to give a bigger role to undrafted rookie Ronnie Wingo.

[27] The Indianapolis Colts signed Choice as a free agent on December 9, 2013, after placing Chris Rainey on the injured reserve list.