The 2006 Western Kentucky Hilltoppers football team represented Western Kentucky University in the 2006 NCAA Division I FCS football season and were led by head coach David Elson.

It was the school's last season as a member of Gateway Football Conference[1] before their transition to the FBS.

[2] The Hilltoppers' schedule was rigorous, with seven ranked opponents, including Georgia.

This team's roster included future National Football League (NFL) players Curtis Hamilton, Dan Cline, and Greg Ryan.

The All-Conference team included Hamilton, Marion Rumph, Dusty Bear, Blake Boyd, Andre Lewis, and Chris Sullivan.