The 2007–08 season was Debreceni Vasutas Sport Club's 15th consecutive season in the Nemzeti Bajnokság I and 105th year in existence as a football club.

In addition to the domestic league, Debrecen participated in this season's editions of the Magyar Kupa, the Ligakupa, the Szuperkupa and the UEFA Champions League.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Source: [1] Source: Competitions Debrecen, as Nemzeti Bajnokság I winners in the previous season, played against Honvéd in the 2008 Szuperkupa, who themselves won the Magyar Kupa.

Source: Hungarian Football Federation