[1] Penn State, who was making their first final four appearance since 1999, finished the season on a 26 match win streak.

Semifinalist California made the program's first NCAA Final Four appearance after upsetting defending champion Nebraska in the quarterfinals.

Overall #1 seed Stanford advanced to the final four for the second straight year with a 3–1 victory over Pac-10 foe UCLA.

[2] The second major upset was unseeded Middle Tennessee defeating 11th seeded Hawai'i in the second round.

Penn State, the #3 overall seed, swept past each opponent to advance to their 6th final four in school history and first since winning the NCAA title in 1999.

[5] Big Ten Freshman of the Year Arielle Wilson was named the regional most outstanding player.

University Park Regional All-Tournament Team: The biggest upset in the NCAA tournament occurred in the Madison regional final, where #10 seed California defeated defending champion and #2 seed Nebraska in a sweep.

[6] Nebraska saw their dominance slipping after having to come up from 2 games down in the regional semifinals against unseeded Michigan State.

Four AVCA All-Americans were named on Penn State's squad, junior Nicole Fawcett, junior Christa Harmotto and sophomore Megan Hodge were named to first team while sophomore Alisha Glass took second team.

Harmotto was named the Big Ten Player of the Year, while freshman Arielle Wilson, who was also named the University Park Regional most outstanding player, was the Big Ten Freshman of the Year.

[11] Coming into the match, Penn State had the highest hitting percentage in the nation as a team, while Stanford was ranked number 4.

The first game started out back at forth with Stanford holding a slight edge at the media timeout at 15–13.

In the third game, Stanford responded and took control of the third, by winning 30–23, and handing Penn State their first single game loss of the tournament, as Penn State swept through each opponent until that point, ending their bid to become just the 3rd school in NCAA history to sweep through each opponent en route to winning the NCAA title.

In the decisive 5th game, Penn State saw Stanford take a 4–3 lead out of Penn State errors, but after that, it was all Nittany Lions as they did not allow Stanford a single kill in a 7–0 scoring run to take their biggest lead of the night at 10–4.