The 2007 Ole Miss Rebels football team represented the University of Mississippi as a member of the Western Division of the Southeastern Conference (SEC) during the 2007 NCAA Division I FBS football season.

Led by Ed Orgeron in his third and final season as head coach, the Rebels compiled an overall record of 3–9 with a mark of 0–8 in conference play, placing last out six teams in the SEC's Western Division.

Ole Miss played home games at Vaught–Hemingway Stadium in Oxford, Mississippi.

Ole Miss travelled to Vanderbilt, Georgia, Arkansas and Mississippi State.

The Rebels hosted SEC opponents Florida, Alabama, Arkansas and LSU.