The 2008 Central League Climax Series (CLCS) consisted of two consecutive series, Stage 1 being a best-of-three series and Stage 2 being a best-of-six with the top seed being awarded a one-win advantage.
The top three regular-season finishers played in the two series.
The CLCS began on with the first game of Stage 1 on October 18 and ended with the final game of Stage 2 on October 25.
The Hanshin Tigers were awarded home-field advantage for the entirety of Stage 1; however, all three games were played in the Orix Buffaloes' Kyocera Osaka Dome, a neutral field, as renovations to Koshien Stadium prevented postseason play.
Yomiuri Giants won the series, 3–1–1*.