The 2008 Blue Square Greyhound Derby took place during May with the final held on 31 May 2008 at Wimbledon Stadium.
After finishing second to Westmead Lord in 2007, Loyal Honcho won the 2008 title in his second attempt, dominating the final.
Seamus Graham's runner, who was sent as the 5–2 joint-favourite along with fellow Irish raider Tyrur Laurel, took control of the race from the traps and pulled clear to beat Tyrur Kieran (11–4) and winner of the Scottish Greyhound Derby, by three and a half lengths in a respectable 28.60 sec (480 metres).
A messy race saw five of the six contenders encounter trouble with Lenson Express falling and finishing last.
It was the first Irish trained success in the Derby since Ian Reilly's Droopys Scholes took the honours in 2004.