The event was hosted at the Family Circle Tennis Center, in Charleston, South Carolina, United States and was the second event of the clay court season, played on green clay courts.

Defending champion Jelena Janković led the field as the number one seed.

Maria Sharapova, Anna Chakvetadze, Elena Dementieva and eventual champion Serena Williams joined her as the other four of five top ten players in the field.

Other notable names that participated were 2007 Wimbledon finalist Marion Bartoli and Charleston standout Patty Schnyder, a two-time runner-up at this event.

Serena Williams defeated Vera Zvonareva, 6–4, 3–6, 6–3 Katarina Srebotnik / Ai Sugiyama defeated Edina Gallovits / Olga Govortsova, 6–2, 6–2