The team was coached by Gary Pinkel, who returned in his eighth season with Mizzou, and played their home games at Faurot Field at Memorial Stadium.

Quarterback Chase Daniel returned for his final year of eligibility and led the Tigers to a second appearance in the Big 12 Championship Game.

[1] Key Losses: Five junior Tigers will return for the 2008 season after turning down the NFL Draft, including QB Chase Daniel, TE Chase Coffman, SS William Moore, Delaware Stryker Sulak and DT Ziggy Hood.

[3] Redshirt freshman DE John Stull was removed from the team on January 11, 2008, after being arrested on drug charges.

Sources: Following their Cotton Bowl Classic victory, Mizzou landed a number of previously committed recruits from the state of Missouri.

[7] From out of state, the Tigers landed OT Dan Hoch, who like Gabbert previously committed to Nebraska.

[8] In a close contest where Missouri held a big lead for most of the game, Illinois cuts it to within 10 near the end but gets no closer.

Missouri takes a commanding 42–0 lead over their FCS competition in their best defensive performance of the year, the first half really showcased their offensive abilities.

Derrick Washington, Jeremy Maclin, and Jeff Wolfert scored for Missouri, and Colin Kaepernick rushed for a 1-yard touchdown for Nevada in the first quarter.

Chase Daniel threw three touchdown passes, Derrick Washington ran for 139 yards and scored three times, as Missouri mopped up Nebraska for their first road win against the Cornhuskers in 30 years (1978).

Oklahoma State handed Missouri their first loss as well as forced their first three and outs all year, giving teams a blueprint on how to slow down the Tigers' "video game offense" which looked unstoppable up to that point.

[13] Like the 2005 game, the 2008 matchup was billed as a battle between two great quarterbacks, Colt McCoy of Texas and Chase Daniel of Missouri having both been mentioned as possible Heisman trophy candidates.

[16] ESPN College GameDay was in Austin for the game, which set a new attendance record (UT, state of Texas, Big12 Conference) of 98,383.

Texas was forced to punt on their first possession of the second half and Missouri scored a touchdown to narrow the lead to 35–10.

[18] ESPN's recap of the game said, "And when McCoy dribbled the ball on the ground only to pick it up and throw a strike that kept the last drive of the half alive, he created the 'Did you just see that?'

[20] Missouri looked good early but barely scraped by Baylor for another flat performance in what was quickly becoming a disappointing season for the Tigers.

On November 30, offensive coordinator Dave Christensen accepted the job as head coach for the Wyoming Cowboys in 2009.

[21] Kansas also got their revenge for having their perfect season ruined the previous year by handing the Tigers their third loss and all but guaranteeing they wouldn't play in a BCS bowl game unless they got a win over Oklahoma.

Former walk-on WR Tommy Saunders moved into sixth place on the MU career receptions list.