The 2008 St. Petersburg Open was a tennis tournament played on indoor hard courts.

It was the 14th edition of the St. Petersburg Open, and was part of the International Series of the 2008 ATP Tour.

4, US Open runner-up, Cincinnati and Madrid Masters, Doha and Marseille winner, St. Petersburg defending champion Andy Murray, Miami Masters, Pörtschach, Warsaw winner Nikolay Davydenko, and Umag titlist Fernando Verdasco.

Also competing were Australian Open quarterfinalist Mikhail Youzhny, New Haven winner Marin Čilić, Dmitry Tursunov, Mario Ančić and Marat Safin.

Andy Murray defeated Andrey Golubev 6–1, 6–1 Travis Parrott / Filip Polášek defeated Rohan Bopanna / Max Mirnyi 3–6, 7–6(7–4), [10–8]