[1] In Round 1 of the 2009 season, Zac Dawson made a surprise debut for St Kilda after being promoted from the rookie list in time to confront Sydney at Docklands[2] as St Kilda defenders Matt Maguire and Max Hudghton were injured.

[6] In round 5, St Kilda restricted Port Adelaide to their second-lowest score in their club history, going down 15.12 (102) to 5.6 (36).

Round 7 saw St Kilda and Collingwood play a Monday night game, the AFL's first for several seasons.

In Round 11 St Kilda won its 11th consecutive game, breaking the previous club record of 10 set in 2004 by beating North Melbourne by 46 points, despite trailing by almost five goals in the first quarter.

The Round 14 clash between St Kilda and Geelong broke the previous record of the largest crowd at an AFL game held at Docklands Stadium with an attendance of 54,444.

Round 20 saw St Kildas first loss of the season proper kicking 16.12 (108) to Essendon 16.14 (110) at Etihad Stadium.