The Argonauts attempted to win their 16th Grey Cup championship, but they failed to make the playoffs for the second straight year, finishing the season with a 3–15 record for the first time since 1993.

The regular season kicked off on July 1 at the Hamilton Tiger-Cats' Ivor Wynne Stadium,[1][2] where the Argos defeated the Ti-Cats 30–17.

The Argonauts had the second overall pick and selected Laval tackle Étienne Légaré, immediately signing him to a three-year contract.

Adriano Belli in particular, who took 4 penalties for 44 yards in the first half including a head butt that continued the Roughriders first drive for a touchdown, took some criticism: "If he wants to be a WWE wrestler, then he can go do that, but he is not going to do on my football team", said Andrus.

On the final play of the third quarter, Stampeders linebacker Dwaine Carpenter stripped the ball from quarterback Kerry Joseph and returned it 55 yards for a touchdown and on the next Argos drive, Calgary defensive back Dwight Anderson intercepted a Joseph pass and ran it back 52 yards for another touchdown to make the score 34 to 9.

Yet another interception later in the fourth quarter by cornerback Brandon Browner gave the Stampeders three defensive touchdowns and a commanding 44 to 9 victory.

[32][33][34] at Rogers Centre, Toronto After a humiliating shutout loss the past week, Cody Pickett was given the job of starting quarterback.

Although the Argos had a lot of trouble finding the endzone throughout the game, kicker Justin Medlock helped them keep the lead by kicking field goals.

On the final play of the game, Ryan Phillips intercepted Reggie McNeal's attempted lateral and returned it for a touchdown.