The competition started on August 25, 2010 and concluded on December 8, 2010 with a two leg final, in which Trujillanos FC won the trophy for the second time with a 0–0 draw at home and a 1–1 draw away over Zamora FC.
NB: Estrella Roja FC decline to take part.
The matches were played on 25–26 August 2010.
The matches were played on 4–5 September 2010.
Trujillanos FC qualify to Copa Sudamericana 2011.