The draw for the opening round fixtures was made on 10 July 2010.

The championship ran from 23 July to 10 October 2010.

Kilmoyley entered the championship as the defending champions, however, they were beaten by Lixnaw in the semi-finals.

Ballyduff won the match by 2–18 to 2–09 to claim a record-equalling 22nd championship title overall and a first title in four years.

[4][5] Lixnaw's James Flaherty was the championship's top scorer with 2-38.