2010 Pacific-10 Conference football season

The 2010 Pacific-10 Conference football season began on September 2, 2010 with a victory by USC at Hawaii.

Conference play began on September 11 with Stanford shutting out UCLA 35–0 in Pasadena on ESPN.

Oregon repeated as the conference champion, ending the regular season with a program-first twelve wins and with a #2 BCS ranking.

The Ducks earned a berth in the 2011 BCS National Championship Game, which they lost to SEC Champion Auburn.

Arizona lost to Oklahoma State while Washington defeated Nebraska in non-BCS bowls.

Michael Thomas (top) was Player of the Week for the Stanford Cardinal in the conference opener against UCLA
Oregon punt returner Cliff Harris scores on a 64-yard punt return against California on November 13 to earn Player of the Week honors.