In 2010 Tipperary claimed their twenty sixth All-Ireland Senior Hurling Championship title after a 4-17 to 1-18 win against Kilkenny in the final at Croke Park, Dublin on 5 September.

[1] On 26 January, Tipperay started the new hurling year with a 1-12 to 0-17 point defeat to Clare in Borrisoleigh in the Waterford Crystal Cup Quarter-Final.

Clare put over many brilliant scorers with Tipperary managing to keep in touch at half time, 0-10 to 0-6.

Liam Sheedy decided to make some changes, bringing on Lar Corbett, Micheal Webster and Noel McGrath.

The first half was evenly fought with both teams hitting over points with Dublin keeping their lead The first sight of the new rules was evident as Dublin got a goal by knocking the ball out of Tipperary goalie Darren Gleeson's hands, which would have been called as a 'square ball' if the new rules were not in place.

With ten minutes to go, A me-lee started by the players escalated into a confrontation between manager's Brian Cody and Liam Sheedy, but the referee Barry Kelly quickly handled the situation.

[citation needed] Tipperary got their third league game underway against Galway in Semple Stadium on 14 March.

The second half began with Limerick player Dean Madden being sent off and then substitute John O'Brien scored Tipperary's second goal, to make it 2-15 to 0-2.

Waterford kept answering back with a well-struck 20 metre free from Eoin Kelly, which landed in the net.

Tipperary led by a point in the closing stages, but Eoin Kelly from Waterford slotted over a free to level it up.

Cork keeper Martin Coleman saved a rasping shot from Lar Corbett with Eoin Kelly failing to put in the rebound.

Two quick points from Paul Kelly resulted in 0-11 tally each, before Gearoid Ryan putting over the leading score.

Cork quickly responded with a shot saved by Brendan Cummins, but a good piece of skill saw Pat Horgan sending in the rebound.

He took the ball and struck it low into the net to give Tipperary a one-point win and third place in the league table.

With 10 minutes remaining, Cork's Jerry O'Connor gave a handpass to a free Aisike O'hAilpin who drove the ball into the net for the killing blow.

Right after the second half began, the game was effectively killed with two goals from Lar Corbett plus two points from play.

Offaly battled hard in the second half, but Tipperary kept putting away the points and never relinquished the lead below 8 points until the final minute of the game, when the Tipperary backs were caught off guard and Offaly slotted home a goal to put the deficit to 6.

Galway gained a three-point lead, but points from Kelly and Brendan Maher brought it down to one before substitute Seamus Callinan blasted home a goal to make it 2-8 to 1-9 at half time.

Galway had more fight in them and gained the lead once more thanks to a goal from Damien Hayes after a bad mistake from Paul Curran.

[12] Tipperary reached the All-Ireland final for their second time in a row to face last year's opponents Kilkenny on 5 September.

Kilkenny began the second half with points from Richie Power and the captain T.J. Reid to level up the game.

However, Kilkenny never led as Tipperary regained points by captain Eoin Kelly before Lar Corbett struck Tipp's second goal in the 41st minute.

The Tipperary team arrived back to Thurles by train on 6 September after the traditional stop at Our Ladies Children's Hospital with the Cup earlier in the day.

They then boarded an open top bus for the journey to the reception at Semple Stadium where an estimated 40,000 supporters turned out to welcome the team home to a rainy Thurles.

[17] Tipperary's Lar Corbett and Brendan Maher were also shortlisted for the GPA Hurler of the Year award for 2010.

On 5 November, Corbett was named as the GPA Hurler of the year for 2010, and received a new Opel Astra car worth €25,000.

[18] [19] Corbett and Maher were joined in the nominations for the GPA team of the year by ten of their Tipperary teammates.

[20] Tipperary won seven places on the GPA team of the year, all of their All Star award winners in addition to Pádraic Maher who was named at left-half back, replacing Kilkenny's JJ Delaney in the only difference to the 2010 All Star team.

Senior substitutes Séamus Hennessy, Brian O'Meara and Michael Heffernan also started for the Under-21 team.

[26][27] In November 2010, Tipperary half back Declan Fanning announced his retirement from inter-county hurling.