The 2010 Villanova Wildcats football team represented Villanova University in the 2010 NCAA Division I FCS football season.

The Wildcats were led by 26th year head coach Andy Talley and played their home games at Villanova Stadium in Villanova, Pennsylvania.

They were a member of the Colonial Athletic Association.

They finished the season 9–5, 5–3 in CAA play.

This college football 2010s season article is a stub.