The season began on 15 July 2011 and ended in May 2012 with Chepo winning the final.
[1] Ten teams completed throughout the season.
Atlético Veragüense finished in 10th place in the overall table last season and were relegated to the Liga Nacional de Ascenso.
Taking their place for this season are the overall champions of last season's Liga Nacional de Ascenso, Colón C-3.
Plaza Amador advances 5–3 on aggregate.