The MLS All-Stars faced Manchester United of the English Premier League for the second year running in the eighth MLS All-Star Game to feature international opposition.

[1] Manchester United won the game 4–0 with goals from Anderson, Park Ji-Sung, Dimitar Berbatov and Danny Welbeck.

The game was played at the Red Bull Arena in Harrison, New Jersey, making it the first MLS All-Star Game to be played in the New York metropolitan area since 1997.

[2] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

♦ – Players selected by MLS Commissioner Don Garber † – Injured and unavailable for matchday ♠ – Unavailable due to FC Dallas playing in the CONCACAF Champions League match the same week of the All Stars game ♥ – "Inactive Roster" players voted for by other players in MLS Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.