The Thundering Herd were led by second-year head coach Doc Holliday and played their home games at Joan C. Edwards Stadium.

In the 2010 season under first year head coach Doc Holliday, the Thundering Herd finished with an overall record of 5–7 and 4–4 within Conference USA.

Once resuming play a Vernard Roberts 1 Yd Run extended the WVU lead to 34–13 early in the 4th quarter, after which the game was once again delayed for lightning.

Rakeem Cato threw three touchdown passes to rally Marshall in a 26–20 win over Southern Mississippi in the Conference USA opener for both teams.

External link: [1] Tyler Tettleton threw for three touchdowns and ran for another, leading Ohio over Marshall 44–7 to cement the Bobcats' best start in 35 years.

Crawford put Marshall ahead with less than two minutes left in the fourth quarter and the Thundering Herd held on to beat Louisville 17–13.

Omar Brown helped seal the victory with an interception of Teddy Bridgewater's pass on the second play of the ensuing drive.

External link: [4] Central Florida running back Brynn Harvey rushed 30 times for 180 yards and quarterback Jeff Godfrey threw his first passing touchdown of the season as the Knights held on to beat Marshall.

Marshall came in with much momentum after an upset win over Louisville the previous week, but struggled to find its offensive footing in steady rainfall throughout the game.

The win ended a two-game losing skid for UCF and gave coach George O'Leary his 100th career victory.

Graham threw two touchdown passes and ran for a score for Marshall, which lost handily despite gaining 506 yards and winning possession time by 24 minutes.

Other than Graham's first-half passing scores, Marshall had another highlight from Omar Brown, who returned an interception 48-yards for a touchdown to give it a 24–0 lead in the second quarter.