[7] The team later agreed to trade the higher of its two fourth-round selections – the pick acquired from the Broncos – to the Seattle Seahawks in exchange for wide receiver Deion Branch.
The Patriots began their 2011 campaign at Sun Life Stadium, for a Week 1 AFC East duel with the Miami Dolphins in the first game of Monday Night Football's doubleheader.
New England took the lead in the second quarter, with quarterback Tom Brady finding tight end Rob Gronkowski on a 10-yard touchdown pass.
The Patriots added onto their lead in the fourth quarter, with a 20-yard field goal from placekicker Stephen Gostkowski, followed by Brady finding Welker on a 99-yard touchdown pass.
After a scoreless third quarter, the Chargers cut into the Patriots lead, with a 3-yard touchdown pass from quarterback Philip Rivers to wide receiver Vincent Jackson.
The Patriots grabbed the lead in the first quarter, with quarterback Tom Brady throwing two touchdown passes – a 14-yarder to wide receiver Wes Welker and a 1-yarder to tight end Rob Gronkowski.
The Raiders narrowed the lead, with a 26-yard field goal by Janikowski, but the Patriots increased it in the fourth quarter, with a 4-yard touchdown pass from Brady to wide receiver Deion Branch.
The Raiders scored a late touchdown, with quarterback Jason Campbell throwing a 6-yard pass to wide receiver Denarius Moore (with a failed two-point conversion attempt), but the Patriots ran out the clock, sealing the win.
The Patriots extended their lead in the third quarter, with quarterback Tom Brady throwing a 2-yard touchdown pass to wide receiver Deion Branch.
The Patriots responded in the second quarter, with a 26-yard field goal by Gostkowski, followed by a 5-yard touchdown pass from quarterback Tom Brady to wide receiver Wes Welker.
The Cowboys narrowed the Patriots' lead just before halftime, with a 1-yard touchdown pass from quarterback Tony Romo to tight end Jason Witten.
The Cowboys tried to rally, but Romo's last-second desperation hail-mary pass toward the end zone was unsuccessful, sealing the win for the Patriots.
New England trailed early in the first quarter, as Steelers quarterback Ben Roethlisberger completed a 5-yard touchdown pass to running back Mewelde Moore.
In the fourth quarter, the Patriots tied the game, with a 5-yard touchdown pass from quarterback Tom Brady to tight end Aaron Hernandez, then took the lead with a 45-yard field goal by Gostkowski.
The Giants re-claimed the lead, with a 10-yard touchdown pass from quarterback Eli Manning to wide receiver Mario Manningham with three minutes remaining.
However, with a minute and a half remaining in a similar repeat of Super Bowl XLII, Manning led the Giants on a game-winning drive, culminating with a 1-yard touchdown pass to tight end Jake Ballard.
It was also the Patriots' first regular season loss at home since November 30, 2008, when they lost to that year's eventual Super Bowl champions, the Pittsburgh Steelers.
The Patriots grabbed the lead in the second quarter, with a 52-yard touchdown pass from quarterback Tom Brady to tight end Rob Gronkowski, followed by a 21-yard field goal by placekicker Stephen Gostkowski just before halftime.
at Gillette Stadium, Foxborough, Massachusetts Coming off their win over the Eagles, the Patriots returned home for an AFC duel with the Indianapolis Colts.
Despite the touchdowns, one of Garçon's catches in the end zone was accompanied with an angry throw at a sign with a target meant for Gronkowski's trademark spike.
The Patriots grabbed the early lead, when defensive tackle Vince Wilfork recovered a fumble off Redskins' quarterback Rex Grossman in the end zone for a touchdown.
Both teams were held scoreless in the fourth quarter, which included linebacker Jerod Mayo intercepting Grossman at the Patriots' 5-yard line with 29 seconds remaining.
In the second quarter Matt Moore raced the Dolphins downfield and connected on touchdowns to Brandon Marshall and Charles Clay for a 17–0 halftime lead.
Moore was sacked on Miami's next possession and the Dolphins had to punt; the Patriots drove down and Tom Brady ran in a quarterback sneak touchdown that tied the game.
at Gillette Stadium, Foxborough, Massachusetts The Bills raced to a 21–0 lead in the first quarter on two Ryan Fitzpatrick touchdown throws and a Tashard Choice four-yard run.
He tied Daryle Lamonica's six scores in the Oakland Raiders' 1969 Divisional round victory over the Houston Oilers and Steve Young's six scores in Super Bowl XXIX over San Diego; his five touchdowns in the first half tied an NFL playoff record with Sid Luckman, Lamonica, Joe Montana, Kurt Warner, Kerry Collins, and Peyton Manning.
A BenJarvus Green-Ellis rushing score, a six-yard Joe Flacco touchdown to Dennis Pitta, and another Gostkowski field goal left the Patriots ahead 13–10 at the half.
Danny Woodhead's fumble of the ensuing kickoff led to another Cundiff field goal, then the Patriots clawed back ahead on a 10-play 67-yard drive ending in a one-yard Tom Brady touchdown leap.
Lee Evans nearly caught a touchdown but the ball was swatted out of his hands in the endzone by Sterling Moore, and with 11 seconds to go Cundiff's 32-yard field goal attempt sailed wide left.
Serving as Patriots co-captains for the opening coin toss were Drew Bledsoe, Tedy Bruschi, Troy Brown, and Ty Law, veterans of the franchise's 1996 Super Bowl season.