The 2011 Santos Brasil Tennis Open was a professional tennis tournament played on clay courts.

It was the first edition of the tournament which was part of the 2011 ATP Challenger Tour.

It took place in Santos, Brazil between 18 and 24 April 2011.

The following players received wildcards into the singles main draw: The following players received entry into the singles main draw as a special exemption: The following players received entry from the qualifying draw: João Souza def.

Diego Junqueira, 6–4, 6–2 Franco Ferreiro / André Sá def.