The 2012 Indianapolis Greyhounds football team represented the University of Indianapolis (UIndy) during the 2012 NCAA Division II football season as a member of the Great Lakes Valley Conference (GLVC).
[1] Led by third-year head coach Bob Bartolomeo, the Greyhounds finished with an overall record of 10–3, going a perfect 8–0 in GLVC play.
The team played its home games at Key Stadium in Indianapolis, Indiana.
The Greyhounds finished the regular season with 9 wins, the most in program history at the time.
The Greyhounds also received their first NCAA Division II playoff berth.