The 2013 Louisville Cardinals baseball team represented the University of Louisville in the 2013 NCAA Division I baseball season.

The Cardinals were coached by Dan McDonnell, in his seventh season, and played their home games at Jim Patterson Stadium.

The Cardinals finished with 51 wins, the most in school history, against 14 losses overall, and 20–4 in the Big East Conference, earning the conference championship.

They reached the College World Series for the second time in their history, where they finished 0–2, eliminated by Oregon State 11–4.

*Denotes non–conference game • Schedule source • Rankings based on the teams' current ranking in the Baseball America poll ^ Collegiate Baseball ranked 40 teams in their preseason poll, but only ranked 30 teams weekly during the season.† NCBWA ranks 35 teams in their preseason poll, but only ranks 30 teams weekly during the season.