The team was coached by Hugh Freeze, who was in his second season with Ole Miss.
The Rebels played their home games at Vaught–Hemingway Stadium in Oxford, Mississippi, and competed in the Western Division of the Southeastern Conference (SEC).
Ole Miss travelled to SEC opponents Vanderbilt, Auburn, Alabama, and ended the season on the road against Mississippi State.
The Rebels played host to Texas A&M, Arkansas, LSU and Missouri.
Ole Miss also travelled to Power 5 foe Texas.