Fifty-two out of the 53 national associations affiliated to CAF entered the qualifying to determine the continent's five slots for the next World Cup.

The ties were drawn at the World Cup Preliminary Draw at the Marina da Glória in Rio de Janeiro, Brazil, on 30 July 2011.

Mozambique DR Congo Togo Liberia Tanzania Congo Kenya Rwanda Ethiopia Namibia Burundi Madagascar Guinea-Bissau Equatorial Guinea Chad Swaziland Comoros Lesotho Eritrea Somalia Djibouti Mauritius Seychelles São Tomé and Príncipe The first legs were scheduled for 11–12 November 2011, with the second legs on 15–16 November 2011.

Ivory Coast Egypt Ghana Burkina Faso Nigeria Senegal South Africa Cameroon Algeria Tunisia Gabon Libya Morocco Guinea Botswana Malawi Zambia Uganda Mali Cape Verde Benin Zimbabwe Central African Republic Sierra Leone Sudan Niger Gambia Angola Kenya† Togo† Namibia† Liberia† Mozambique† Equatorial Guinea† Ethiopia† Lesotho† Rwanda† DR Congo† Congo† Tanzania† † First round winners whose identity was not known at the time of the draw Cameroon were suspended by FIFA on 4 July 2013 for government interference.

[10][11] Ivory Coast (19) Ghana (24) Algeria (28) Nigeria (36) Tunisia (46) Egypt (50) Burkina Faso (51) Cameroon (61) Senegal (66) Ethiopia (93) The matches were played in the periods of 11–15 October and 16–19 November 2013.