The 2015–16 Charlotte 49ers women's basketball team represented the University of North Carolina at Charlotte during the 2015–16 NCAA Division I women's basketball season.

The 49ers, led by fourth year head coach Cara Consuegra, played their home games at Dale F. Halton Arena and were members of Conference USA.

They lost in the quarterfinals of the C-USA women's tournament to Old Dominion.

They were invited to the Women's National Invitation Tournament, where they lost to Wake Forest in the first round.

Cara Consuegra (Iowa) Joanne Aluka-White (Middle Tennessee)Randi Henderson (Iowa) Nicole Woods (Belmont Abbey) Roster [1] 2015–16 Charlotte 49ers men's basketball team