The 2015–16 Florida Gulf Coast Eagles women's basketball team represented Florida Gulf Coast University (FGCU) in the 2015–16 NCAA Division I women's basketball season.

The Eagles, led by fourteenth year head coach Karl Smesko, played their home games at Alico Arena and were members of the Atlantic Sun Conference.

They advanced to the championship game of the A-Sun women's tournament, where they lost to Jacksonville.

They received an automatic bid to the Women's National Invitation Tournament, where they advanced to the championship game where they lost to South Dakota.

Road games will also be broadcast on the FGCU Portal.