The 2015–16 George Mason Patriots women's basketball team represented George Mason University during the 2015–2016 College Basketball season.

The Patriots, led by third year head coach Nyla Milleson.

The George Mason Patriots are members of the Atlantic 10 Conference and play their home games at EagleBank Arena.

They advanced to the quarterfinals of the A-10 women's tournament where they lost to George Washington.

Roster [1] 2015–16 NCAA Division I women's basketball rankings