The 2015–16 Marshall Thundering Herd women's basketball team represented the Marshall University during the 2015–16 NCAA Division I women's basketball season.

The Thundering Herd, led by third year head coach Matt Daniel, played their home games at the Cam Henderson Center and were members of Conference USA.

They finished the season 17–15, 8–10 for in C-USA play to finish in a tie for sixth place.

They advanced to the semifinals of the C-USA women's tournament, where they lost to Middle Tennessee.

They were invited to the Women's National Invitation Tournament, where they lost in the first round to Ohio.