The 2015–16 Niagara Purple Eagles women's basketball team represented Niagara University during the 2015–16 NCAA Division I women's basketball season.
The Purple Eagles, led by first year head coach Jada Pierce, played their home games at the Gallagher Center and were members of the Metro Atlantic Athletic Conference.
They finished the season 8–22, 5–15 in MAAC play to finish in a tie for ninth place.
They advanced to the quarterfinals of the MAAC women's tournament, where they lost to Quinnipiac.
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