The 2015–16 Northwestern State Lady Demons basketball team represented Northwestern State University during the 2015–16 NCAA Division I women's basketball season.

The Demons, led by fourth year co-head coaches Brooke Stoehr and Scott Stoehr, played their home games at Prather Coliseum and were members of the Southland Conference.

They lost in the semifinals of the Southland women's tournament to Sam Houston State.

Many opponents have an audio stream available to listen to the games live that aren't done on Demons Showcase.

NSU TV will also broadcast most of the Lady Demons wins tape delayed.