The 2015–16 Tunisian Ligue Professionnelle 2 (Tunisian Professional League) season was the 61st season since Tunisia's independence.
The first three of each group will qualify to the promotion playoff, while the last of each group will be relegated to Ligue 3.
The two teams that finish the regular season in the 9th position will play a relegation playoff, a single match to determine who is maintained in Ligue 2 and who is relegated to Ligue 3.
US Monastir, AS Gabès and AS Djerba were the three relegated teams at the end of the 2014-15 Ligue 1 season.
On the other hand, STIR Zarzouna, US Siliana and US Tataouine were the three promoted teams at the end of the 2014–15 Ligue 3 season.